Lorenzo Sansone (1881-1975) was born in Monte Santagelo, Italy. Since his father did not support his early interest in music he learned how to make his own instruments and taught himself how to play them. At age ten he began playing fluegelhorn in the town band and at age thirteen he was hired to play horn in a band in San Severo. In 1903, Sansone emigrated to the United States and was hired immediatly by Chiafferellis Italian Band. In 1906 he became the conductor of the Ventura California City Band where he engaged in composing and arranging as well. Upon leaving Ventura, Sansone took up a career playing with a number of orchestras from coast to coast., often describing himself as solo horn whether actually principal or not: Los Angeles (ca. 1906), Denver (1909-1910), St. Paul (1911), St. Louis (1912-1915), Chicago (summer 1914), Cincinnati (1915-1916, 1917-1918), Chicago Opera (1916-1917), Detroit (1918-1919), New York Symphony (1920-1922), Beethoven Symphony Orchestra (1927- ?), National Broadcasting Orchestra (1929-?) , and Metropolitan Opera (1931-1933).

Lorenzo Sansone was a prolific composer, publisher, and arranger of music for horn. In 1961 all of his copyrights were sold to Southern Music Company. He taught nearly 300 students in his tenure at the Julliard School from 1921 to 1946. Thereafter he maintained his own private studio with many of his students going on to professional careers.